Sorrento announces publication of data in Cell Press Journal Med describing the discovery and preclinical efficacy of a broad-acting SARS-CoV-2 neutralizing antibody administered IV (STI-9167) or IN (STI-9199)
SAN DIEGO, Oct. 14, 2022 (GLOBE NEWSWIRE) — Sorrento Therapeutics, Inc. (Nasdaq: SRNE, “Sorrento”) today announced the publication in Cell Press journal Medium of data detailing work related to the discovery and preclinical profiling of the activity of neutralizing antibodies STI-9167 against a large collection of SARS-CoV-2 variants, including some Omicron subvariants. Protection against illnesses linked to Omicron live in a preclinical challenge model was observed after administration of STI-9167 intravenously (IV) or after intranasal (IN) administration using an intranasal formulation of STI-9167 antibody, designated STI-9199.
A link to the publication is below:
About Sorrento Therapeutics, Inc.
Sorrento is a clinical and commercial-stage biopharmaceutical company developing novel therapies to treat cancer, pain (non-opioid treatments), autoimmune diseases and COVID-19. Sorrento’s multi-modal, multi-pronged approach to fighting cancer is enabled by its extensive immuno-oncology platforms, including key assets such as next-generation tyrosine kinase (“TKI”) inhibitors, fully human antibodies (“G-MAB™ library”), cell therapies (“DAR-T™”), antibody-drug conjugates (“ADCs”) and oncolytic viruses (“Seprehvec™”). Sorrento is also developing potential antiviral therapies and coronavirus vaccines, including STI-1558, COVISHIELD™ and COVIDROPS™; and diagnostic testing solutions, including COVIMARK™.
Sorrento’s commitment to therapies that improve the lives of patients is also demonstrated by our efforts to advance a non-opioid pain management small molecule (TRPV1 agonist), resiniferatoxin (“RTX”) and SP-102 (10 mg, dexamethasone sodium phosphate viscous gel) (SEMDEXA™), a new viscous gel formulation of a corticosteroid widely used for epidural injections to treat lumbosacral radicular pain or sciatica, and to market the ZTlido® (topical lidocaine system) 1.8% for the treatment of postherpetic neuralgia (PHN) . RTX has been cleared for a phase II trial in intractable pain associated with cancer and a phase II trial in patients with osteoarthritis. Positive final results from the CLEAR program of the pivotal Phase III trial for SEMDEXA™, its new non-opioid product for the treatment of lumbosacral radicular pain (sciatica), were announced in March 2022. ZTlido® was approved by the FDA on February 28, 2018.
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Contact: Brian Cooley
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Sorrento® and the Sorrento logo are registered trademarks of Sorrento Therapeutics, Inc.
G-MAB™, DAR-T™, Seprehvec™, SOFUSA™, COVISHIELD™, COVIDROPS™, COVI-MSC™, COVIMARK™ and Fujovee™ are registered trademarks of Sorrento Therapeutics, Inc.
SEMDEXA™ (SP-102) is a registered trademark of Semnur Pharmaceuticals, Inc. Proprietary name review by the FDA is pending.
ZTlido® is a registered trademark owned by Scilex Pharmaceuticals Inc.
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