Electrolyte consumption by preterm infants in their first week of life is higher
For one study, researchers sought to determine how very low birth weight infants (VLBW,
All TLBW children born before (n = 81) and after (n = 53) the start of a concentrated NP regimen were included in the single center cohort search. Clinical records were used to collect daily dietary intakes as well as plasma concentrations of calcium, potassium, phosphate, sodium and chloride.
Infants who received concentrated PN consumed more electrolytes during the first postnatal week than infants who received original PN. Hypokalaemia (P P=0.02) were less common in infants who received concentrated PN. While phosphorus intake below the recommended level may explain the relatively high frequency of severe hypophosphatemia in babies who initially had PN, potassium intake during the first three postnatal days (mean ± SD: 0.7 ± 0.2 mmol/kg/d) was within the recommended range. The difference in salt intake between the 2 groups had no impact on the prevalence of early hypernatremia.
During the first days of life, a solution of PN containing sodium (approximately 2.7 mmol/100 ml) does not induce hypernatremia in LBW neonates. In addition, to avoid early hypokalaemia, it may be important to provide at least 1 mmol of potassium/kg/d during the first 3 postnatal days.